Dendrimer and nanostructuresupported carboranes and. These metrics are regularly updated to reflect usage leading up to the last few days. Carboranes are electrondelocalized nonclassically bonded clusters composed of boron. Herein, the reversible conversion of catalytically infeasible ocarboranyl methylamines 1ch2nh2ocarb most popular 20182019 main group, inorganic and organometallic chemistry articles.
Electrochemistry and photoluminescence of icosahedral. Any of a class of stable crystalline compounds composed of carbon, boron, and hydrogen. Like many of the related boron hydrides, these clusters are polyhedra or fragments of polyhedra, and are similarly classified as closo, nido, arachno, hypho, etc. Diborane is a colorless gas with a repulsive, sweet odor. A large number of metallacarboranes with vertices or more possessing very rich structural diversities have been prepared via different synthetic routes using various types of carboranyl ligands.
Carboranes, third edition, by russell grimes, is the definitive resource on the subject. Inner shell electron energyloss spectroscopy of boranes and carboranes boron 1s iseels of nidopentaborane 9, 1, nido2,3 diethy. Results and discussion to create a new carboranebased mof with a large pore volume and surface area, a relatively long boronrich ligand was synthesized that consists of a central pcarborane unit and two isophthalic acid groups lh4scheme 1. New sulfur derivatives of carboranes and metallacarboranes.
Syntheses of icosahedral closodicarbadodecaborane derivatives r 2 c 2 b 10 h 10 employ alkynes as the r 2 c 2 source and decaborane b 10 h 14 to supply the b 10 unit tricarba, tetracarba, pentacarba, and hexacarba clusters. We have looked at the reduction of phospha and arsacarboranes with sodium metal. Further, there is evidence that the use of substituted derivatives could provide. Metallacarbaboranes or metallacarboranes are a class of inorganic polyhedral clusters. Boranes, carboranes, metalloboranes, transition metal carbonyls and other cluster formulas obey the law of skeletal numbers and their valences bipyramid one and 116 an octahedral shape 18. Because diborane is a gas a ambient temperature, the mostlikely exposure routes are inhalation. It is used in rocket propellants and as reducing agent, as a rubber vulcanizer, as a catalyst for olefin polymerization, as a flamespeed accelerator, and as a doping agent. Pdf electrochemistry and photoluminescence of icosahedral. Carboranes definition of carboranes by the free dictionary. Carborane, any member of a class of organometallic compounds containing carbon c, boron b, and hydrogen h. Efforts of half a century in this research area have led to the extensive studies on the chemistry of carboranes and metallacarboranes. However, direct cage boron derivation of these carborane derivatives has not been solved. Functionalization of the multiple, similar, boronhydrogen bonds in carboranes is difficult to achieve with selectivity. Department of chemistry and biochemistry, northern illinois university, dekalb.
Recent developments in the study of carboranes hawthorne has recently demonstrated that the dianion is an opencage species by converting it to the transition metal complex, b10h10c2h2coc5h520. From nonpeptide toward noncarbon protease inhibitors. The delivery of carboranes in the bnct of cancers patras, greece, 4th of july 20 drug discovery, delivery and patient care dddpc research hub faculty of science, engineering and computing, kingston university. Carboranes synonyms, carboranes pronunciation, carboranes translation, english dictionary definition of carboranes. Fusionner pdf combiner en ligne vos fichiers pdf gratuitement. Carborane acids are so strong that they protonate or react with almost every solvent. Carboranes having more than two carbon atoms in the skeletal framework, obtained in a variety of ways, include derivatives of nidoc 3 b 3 h 7, nidoc 3 b 8 h 11. Carboranes larger than 14 vertexes containing only carbon and boron in the skeletal framework have not been prepared, but zhang et al. Safety data sheet ghs product identifier other means of identification emergency telephone number with hours of operation section 1. Pdf icosahedral boranes, carboranes, and metallacarboranes are extraordinarily robust. Carboranyl derivatives of platinum and tin and some metallacarboranes exhibit activity against malignant tumors.
Transition metal derivatives ofpolyhedral boranes and carboraneshan songdepartment of chemistrypenn state universitychem 516 presentation12012 2. Inorganic chemistry3 metalcomplexes and metal clusters module. Performance tests indicated that carboranes are excellent materials for obtaining high uniform loadings of boron inhibitors in glassy carbon materials and thus reducing their rates of oxidation. The examples described in this manuscript highlight some recent developments demonstrating how carboranes and metallacarboranes have been successfully employed as organomimetic substituents within several ligand platforms fig. Carborane definition of carborane by the free dictionary. The medicinal chemistry of dicarbaclosododecaboranes otherwise referred to as carboranes has traditionally centered on their use in boron neutron capture therapy bnct. Multidentate carboranecontaining lewis acids and their.
Learn more about these metrics article views are the countercompliant sum of full text article downloads since november 2008 both pdf and html across all institutions and individuals. Gassorption properties of cobalt iicarboranebased coordination polymers as a function of morphology are discussed. One common measure of acid strength for concentrated, superacidic liquid media is the hammett acidity function, h 0. Carboranes are electrondelocalized clusters composed of boron, carbon and hydrogen atoms that may also contain other metallic and nonmetallic elements in the cluster framework. Carboranes as guests, counterions and linkers in coordination polymers and networks catherine e. These examples demonstrate how properly designed carborane derivatives, by virtue of their enhanced stability. Multidentate carboranecontaining lewis acids and their chemistry. Icosahedral boranes, carboranes, and metallacarboranes are extraordinarily robust compounds with desirable properties such as thermal and redox stability, chemical inertness, low nucleophilicity, and high hydrophobicity, making them attractive for several applications such as medicine, nanomaterials, molecular electronics, energy, catalysis, environmental chemistry, and other areas. Boron neutron capture therapy bnct applications the chemistry of bnct. New ligand platforms featuring boronrich clusters as. The use of carboranes and metallacarboranes in materials science is receiving unprecedented attention. The borane fragments and clusters of nuclearity b 1 to b 12 have been derived using skeletal numbers and valences. Synthesis, characterization, and thermal behavior of. Oxidation of the products regenerates neutral phospha and.
Tjarks, carborane clusters in computational drug design. Metallacarborane complexes, incorporating one or more metal atoms within. Compound 1 and cobalt ii salts were used successfully to synthesize three new coordinationpolymer materials simply by varying the reaction solvent and temperature conditions. Chyan, synthesis, radioiodination, and biodistribution of some nido and closomonocarbon carborane derivatives, nuclear medicine and biology, vol. Here the authors report an iridiumcatalysed borylation ofocarboranes with. It is found that these triad molecules can harvest both s1 and t1 excitons and display thermally activated delayed fluorescence12 through upconversion from nonradiative t 1 excitons into emissive s1 excitons in their aggregated states. Carborane article about carborane by the free dictionary. The role of homogeneous and heterogeneous carborane and metallacarborane catalysts in a variety of organic reaction types including hydrogenation, hydrosilylation, polymerization.
Most of the carborane derivatives of the icosahedral c2b10 or small cage c2b4 systems are formed, by varying the groups on the cage carbons. A series of new closo and nidocarborane based thioethers with exopolyhedral carbonsulfur bond 1xch2ns1,2c2b10h11 x cooh. The layer of carboranes changes the geometry and stability of the material beneath. We decided to combine ec and pl of boron clusters because both processes are related in the sense. Pdiicatalyzed synthesis of bifunctionalized carboranes. Structure and bonding of carboranes the formulas of typical closo nido and arachnoboranes and carboranes are listed in boron e. The altmetric attention score is a quantitative measure of the attention that a research article has received online. The borane clusters and their relatives strictly obey the law of skeletal numbers and valences. Icosehedral carboranes are frequently used for preparation of high temperature resistant polymers,1,8 boroncontaining macromolecules for boron neutron capture therapy, bnct,8,9 and luminescent copolymers with a large system of conjugated electrons. Carboranes article about carboranes by the free dictionary. In coordination chemistry, it is used as unique bulky ligand scaffolds. Recent advances in the chemistry of carboranes and. One of the b or c atoms in carboranes can be replaced by one atom of another element, such.
Icosahedral boranes, carboranes, and metallacarboranes are extraordinarily robust compounds with. Based on its ability to quantitatively protonate benzene, the chlorinated carborane acid hchb 11 cl 11 was conservatively estimated to have an h 0 value at or below. Structure boranes and carboranes metallocarboranes. The concept of raw skeletal structures which directly produce the parental cluster formulas has been introduced. Other articles where metallacarborane is discussed. Metalcontaining carboranes with antitumor activity. Housecroft department of chemistry, university of basel, spitalstrasse 51, 4056 basel, switzerland email. Carboranes, second edition is designed as a comprehensive source of information in a field that has experienced enormous growth in both its fundamental and applied aspects in the four decades since the publication of carboranes 1970. Aminoalkyl carboranes are anticipated to be valuable synthons toward the synthesis of bifunctionalized carboranes. Title metallacarboranes and their interactions nui galway.